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January 2009 Off the Wire . . .



01-03-09 CXCL1 Decreases Severity Of Multiple Sclerosis-like Disease
MS Trust Favourite, Mr Motivator Set To Motivate The Nation
A Protein That Protects Against Alzheimer's?
ArGentis Receives Favorable Opinion For European Orphan Drug Designation
Evaluation Of The Safety And Efficacy Of Sildenafil Citrate For Erectile Dysfunction In Men With Multiple Sclerosis
Cold Weather Payment - Are You Eligible? UK
New Interferon Formulations Promise To Eliminate Injections In Multiple Sclerosis Treatment
Relapses More Frequent In Patients Diagnosed With Pediatric-Onset Multiple Sclerosis
MS Society Statement: Personal Budgets In Healthcare, UK
01-16-09 MS Society Welcomes Personal Budgets In Healthcare; UK
MS Trust Welcomes Individual Patient Budgets, UK
MS Trust Welcomes Moves To More Personalised Health And Care Services
Cladribine, an experimental oral drug for relapsing MS is effective in reducing the number of relapses experienced according to new research reported today.
[read article]
Biologists ID Gene, Pathway For Nerve Regeneration In Worms, Offering Hope For Restoring Injured Nerves
University of Utah scientists identified a worm gene that is essential for damaged nerve cells to regenerate, and showed they could speed nerve regeneration by over-activating the gene - a step toward new treatments for nerves injured by trauma or disease.
[read article]
MS Society Adverts - Seeking More Stories And More Models!
The MS Society is planning its next national advertising campaign for MS Week 2009 (27 April to 3 May). After the success of the 2008 campaign a similar visual style and approach is set to be adopted for MS Week - and as with the last campaign in 2008, we need your stories.  [read article]
Cladribine Trial Results, Multiple Sclerosis
Cladribine, an experimental oral drug for relapsing MS is effective in reducing the number of relapses experienced according to new research reported today. The trial, called CLARITY, was a two year study involving 1,326 people with relapsing/remitting MS receiving one of two doses of cladribine or an inactive placebo. [read article]
NICE Issues Guidance On FES For Dropped Foot
NICE (the National Institute for Health and Clinical Excellence) has issued guidance that says FES (functional electrical stimulation) is safe and can be considered for use in the NHS as a treatment for dropped foot. [read article]
Spinal Fluid Proteins Signal Lou Gehrig's Disease
High levels of certain proteins in the spinal fluid could signal the onset of Lou Gehrig's disease, according to researchers. The discovery of these biomarkers may lead to diagnostic kits for early diagnosis, accurately measuring the progression of the disease and monitoring the effects of treatment. [read article]
Scientists Reverse Early MS With Patients' Own Stem Cells
A small trial at a US hospital where patients with early stage MS had their own immune system stem cells transplanted back into their bodies appears to have reversed the neurological dysfunction of the early stages of the disease by causing their immune systems to "reset".
[read article]
Stem Cell Transplant Trial Results - Comment By The Multiple Sclerosis Society
Ahead of the publication on Friday 30 January of a paper in The Lancet Neurology reporting the results of a trial involving stem cell transplantation in people with relapsing remitting multiple sclerosis (MS), please find below a comment from the MS Society: Dr Doug Brown, Research Manager at the MS Society, said: "These are very encouraging results and it's exciting to see that in this trial not only is progression of disability halted, but damage appears to be reversed.
[read article]
Teaching An Old Drug New Tricks
A century-old drug that failed in its original intent to treat tuberculosis but has worked well as an antileprosy medicine now holds new promise as a potential therapy for multiple sclerosis and other autoimmune diseases.
[read article]
Early-Stage Multiple Sclerosis Reversed By Stem Cell Transplant
Researchers from Northwestern University's Feinberg School of Medicine appear to have reversed the neurological dysfunction of early-stage multiple sclerosis patients by transplanting their own immune stem cells into their bodies and thereby "resetting" their immune systems.
[read article]

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